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. 2021 May 25;22:160. doi: 10.1186/s13059-021-02381-4

Fig. 5.

Fig. 5

Functional enrichment of mutated genes in MA lines and populations. a GO enrichment of mutated genes in the Control (A and D), Heat (B and E), and Warming (C and F) treatments. The arrow indicates an important biological process. b Expression levels of mutated genes under Heat and Warming differed significantly from the Control (expression dataset obtained from NCBI GSE118298). Log10-transformed FPKM expression values for each treatment were visualized using a heatmap. Red color indicates a high expression level, and blue color indicates a low expression level. c Nonsynonymous (orange), frameshift deletion (blue), frameshift insertion (yellow), and stop gain (grey) mutations in gene coding regions of MA lines and populations. Each gene involved in a putative biological process is shown. Defense response- and DNA repair-associated genes are marked in blue, and asterisks indicate the differentially expressed genes shown in (b)