Table 3.

Plasmids delivery and virus infection regimen.

	Group
	P + V	P	N + V	N	C + V	C
Plasmid	pSil-double-shRNA-N1-mcherry	pSil-double-shRNA-N1-mcherry	pSil-shRNA-NC-mcherry	pSil-shRNA-NC-mcherry	PBS	PBS
Vector dosage	3 mg/1 mL/piglet	3 mg/1 mL/piglet	3 mg/1 mL/piglet	3 mg/1 mL/piglet	1 mL/piglet	1 mL/piglet
PDCoV	PDCoV	PBS	PDCoV	PBS	PDCoV	PBS
Viral dosage	105 TCID50/10 mL/piglet	10 mL/piglet	105 TCID50/10 mL/piglet	10 mL/piglet	105 TCID50/10 mL/piglet	10 mL/piglet