Figure 5.
Components of a first-generation CAR. A CAR is made up of the ectodomain (composed of a scFv and hinge), the transmembrane domain and the intracellular signaling endodomain. Abbreviations: scFv; single-chain variable fragment.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.