ASC	apoptosis-associated speck-like containing a CARD
CAIA	collagen antibody-induced arthritis
CAPS	cryopyrin-associated periodic syndromes
CARD	caspase activation and recruitment domain
caspase	cysteine-dependent aspartic acid-specific protease
CD	Crohn’s Disease
cFLIP	cellular FLICE-like inhibitory protein
cIAP	cellular inhibitor of apoptosis protein
CRIA	cleavage-resistant RIPK1-induced autoinflammatory syndrome
CYLD	cylindromatosis
DAI	DNA-dependent activator of IFN regulatory transcription factors
DAMP	damage-associated molecular pattern
DNA	deoxyribonucleic acid
EDA-ID	ecto-dermal dysplasia with immunodeficiency
ER	endoplasmic reticulum
GI	gastrointestinal
GSDMD	gasdermin D
HA20	haploinsufficiency in A20
HLH	hemophagocytic lymphohistiocytosis
HMGB1	high-mobility group box 1
HOIL-1	haeme-oxidized IRP2 ubiquitin ligase 1
HOIP	HOIL1-interacting protein
HSP	heat shock protein
IBD	inflammatory bowel disease
IAV	Influenza A virus
IEC	intestinal epithelial cell
IFN	interferon
IL	interleukin
IMQ	imiquimod
LOF	loss of function
LRR	leucine-rich repeat
LUBAC	linear ubiquitin chain assembly complex
MAPK	mitogen-activated protein kinase
MDP	muramyl dipeptide
MLKL	mixed lineage kinase domain-like
NEMO	NF-κB essential modulator (IKK)
NF-κB	nuclear factor-kappa B
NLR	NOD-like receptor
NLRP3	NOD-like protein receptor 3
NOD	nucleotide-binding oligomerization domain
NSA	necrosulfonamide
PAMP	pathogen-associated molecular pattern
PRR	pattern recognition receptor
RA	rheumatoid arthritis
RIPK	receptor-interacting protein kinase
RNA	ribonucleic acid
ROS	reactive oxygen species
RSV	respiratory syncytial virus
SHARPIN	SHANK-associated RH domain-interacting protein
PTPN6	protein tyrosine phosphatase-6
SMAC	second mitochondrial activator of caspases
SM	Smac mimetic
TAK1	transforming growth factor—activated kinase
TLR	Toll-like receptor
TNF	tumour necrosis factor
TNFR	tumour necrosis factor receptor
TRADD	TNFR1-associated death domain protein
TRAF2	TNF receptor-associated factor 2
TRAIL	TNF-related apoptosis-inducing ligand
TRAPS	TNFR-associated periodic syndrome
TRIF	TIR-domain-containing adapter-inducing interferon-β
UC	ulcerative colitis
VEO	very-early onset
XIAP	X-linked inhibitor of apoptosis protein
XPL2	X-linked lymphoproliferative disease 2
ZBP1	Z-DNA binding protein 1