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. 2021 Apr 23;8(5):50. doi: 10.3390/bioengineering8050050

Table 1.

Stem cell niches which have been studied for their potential to improve tissue regeneration by controlling stem cell behavior.

Tissue/System Location Stem Cell Population Ref
Skin Hair follicles Melanocyte stem cells, Hair follicle dermal papilla cells [21,22]
Rete ridges Epidermal stem cells [23]
Keratinocyte stem cells [24]
Hematopoietic system Bone marrow Hematopoietic stem cells (HSCs) [25]
Mesenchymal stem cells (MSC) [26]
Small intestine Epithelium of the small intestine Intestinal stem cells, non-epithelial stromal cells, myofibroblasts. [27]
Heart Epicardial lining Cardiac stem cells (CSC) [28]
Myocardium
Cartilage Articular cartilage Bone marrow Mesenchymal stem cells (BMSC), Cartilage-derived mesenchymal progenitors [29]
Eye Corneal limbus/Palisades of Vogt Limbal epithelial stem cells [30]
Neural system Subventricular zone Neuronal stem cells (NSC) [31,32]
Hilus of the dentate gyrus Radial neural stem cells, Dentate gyrus neural stem cells [33]
Lung Lung epithelium/tracheal submucosal glands Basal cells, club cells, and alveolar epithelial cells type II cells. [34,35]
Primary or permanent teeth Dental pulp tissue Human dental pulp stem cells, MSCs, BMSCs. [36,37]