Table 5.

Summary of electrospun constructs used to recreate the micro and nano spatial cues of the stem cell niche.

Application	Polymer	Outcome	Ref
Study adhesion and expansion of hHSCs	Polyethersulfone (PES) aminated using acrylic acid	Non-woven PES nanofiber meshes of 529 ± 114 nm in diameter.	[159]
Study the effects of fiber diameter on NSC differentiation and proliferation	Laminin-coated PES mats	Electrospun fiber meshes with average diameters of 283 ± 45 nm, 749 ± 153 nm, and 1452 ± 312 nm	[160]
Observe the sensibility of NSCs when exposed to an aligned topography	PCL fibrous mats coated with polyornithine and laminin	Aligned electrospun fibers with average diameters of 251, 472, 923 nm, and random fibers of 269, 481, 934 nm.	[161]
Study the influence of transplanting MSCs and ESCs in re-epithelization	Silk fibroin protein/gelatin polymer solution	Random or aligned uniform bead-less fibers with diameters of 63.1 ± 2.7 nm	[162]