Fig. 15.

Schematic representation of dendritic cell targeting strategy using bifunctional fusion protein (bfFp). The bfFp is a recombinant fusion protein consisting of truncated core-streptavidin fused with anti-DEC-205 single chain antibody (scFv). The core-streptavidin arm of fusion protein binds with biotinylated nanoparticles while anti-DEC-205 scFv imparts targeting specificity to DC DEC-205 receptor. Reprinted with permission.