Table 3.
Clinical statuses and GAS5 rs145204276 genotype frequencies in oral cancer.
| Variables | GAS5 (rs145204276) | |||
|---|---|---|---|---|
| Ins/Ins (%) (n = 460) | Ins/Del + Del/Del (%) (n = 665) |
OR (95% CI) | p Value | |
| Clinical Stage | ||||
| Stage I/II | 231 (50.2%) | 298 (44.8%) | 1.00 | p = 0.074 |
| Stage III/IV | 229 (49.8%) | 367 (55.2%) | 1.242 (0.979–1.577) | |
| Tumor size | ||||
| ≤T2 | 245 (53.3%) | 337 (50.7%) | 1.00 | p = 0.394 |
| >T2 | 215 (46.7%) | 328 (49.3%) | 1.109 (0.874–1.407) | |
| Lymph node metastasis | ||||
| No | 310 (67.4%) | 435 (65.4%) | 1.00 | p = 0.490 |
| Yes | 150 (32.6%) | 230 (34.6%) | 1.093 (0.849–1.406) | |
| Distant metastasis | ||||
| No | 453 (98.5%) | 661 (99.4%) | 1.00 | p = 0.123 |
| Yes | 7 (1.5%) | 4 (0.6%) | 0.392 (0.114–1.346) | |
| Cell differentiation | ||||
| well | 79 (17.2%) | 83 (12.5%) | 1.00 | p = 0.028 * |
| Moderate/poor | 381 (82.8%) | 582 (87.5%) | 1.454 (1.041–2.031) | |
* denotes significant difference of clinicopathological characteristics between the different GAS5 rs145204276 genotypes.