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. 2021 Apr 23;13(5):614. doi: 10.3390/pharmaceutics13050614

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Cell viability and inflammation study. (A) Time-dependent cytotoxicity of PVP, PVP/Lipo, and PVP/Lipo + EVL. (B) Live and dead assay to visualize cytotoxicity of coating materials (Scale bars equal to 400 μm). (C) ELISA assay to confirm level of pro-inflammatory (IL-6) and anti-inflammatory (IL-10) factors in HCASMCs incubating with bare Nylon tube, PVP, PVP/Lipo, and PVP/Lipo + EVL. Values are presented as mean ± SD (n = 3) and statistical significance was obtained with one-way analysis of ANOVA with Tukey’s multiple comparison post-test (n.s: non significancy; ** p < 0.01; *** p < 0.001).