Table 9.

Mean biomarker gene expression at 15 weeks of exposure to sulforaphane by presence or absence of fever effect (natural log transformed values for change from baseline)

	Fever effect N	Fever effect Mean (95% CI)	No fever effect N	No fever effect Mean (95% CI)	p value†
NQO1	16	0.33 (− 0.34, 1.00)	20	0.93 (0.26, 1.60)	0.196
xCT	17	− 0.24 (− 0.72, 0.23)	21	0.51 (0.02, 0.99)	0.027
HO-1	17	− 0.45 (− 1.08, 0.18)	21	− 0.40 (− 1.07, 0.28)	0.906
HSP70	17	0.02 (− 0.22, 0.26)	21	− 0.35 (− 0.60, − 0.09)	0.037
HSP27	17	− 0.52 (− 1.12, 0.08)	21	− 0.70 (− 1.42, 0.02)	0.697
IL-6	17	− 1.59 (− 2.21, − 0.98)	20	− 0.98 (− 1.69, − 0.27)	0.187
IL-1β	16	− 0.61 (− 1.27, 0.06)	20	− 1.12 (− 2.22, − 0.02)	0.434
COX-2	17	0.08 (− 0.26, 0.41)	21	− 0.36 (− 0.55, − 0.18)	0.015
TNF-α	17	− 0.30 (− 0.68, 0.07)	21	− 0.89 (− 1.32, − 0.46)	0.043

Bold signifies p < 0.05

p value based on t test