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In vivo tumor formation assays validate the function of circ-PTK2 in tumorigenesis. A Tumors collected from euthanized nude mice. B Amounts of nodules present. C Tumor volume. D Hematoxylin and eosin staining of cellular structure and immunohistochemical staining to determine the protein level of E-cadherin and N-cadherin. Data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001
