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IgG, IgG subclasses, and IgM antibody responses in sera. Sera collected from mice post-immunization were used to assess the T. gondii-specific antibody responses. The levels of IgG (A), IgG1 (B), IgG2a (C), IgG2b (D), and IgM (E) antibody responses in the CpG-adjuvanted TG146 VLPs were higher than those from the TG146 VLPs alone. The data are expressed as mean ± SD, and statistical significance is denoted using asterisks (* p < 0.05, ** p < 0.01, *** p < 0.001).
