Figure 7.

Protective efficacy induced by VLP immunizations. The VLP-immunized mice were challenge-infected with T. gondii (ME49), and the mice were sacrificed 30 dpi for brain tissue collection. The adjuvanted VLP immunization showed significantly lower levels of inflammatory cytokine TNF-α (A) compared to unadjuvanted VLPs alone. The cysts in the brain were counted (B) and the bodyweight loss was determined (C). The data are expressed as the mean ± SD, and statistical significance is denoted using asterisks (* p < 0.05, ** p < 0.01).