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. 2021 Apr 28;7(5):343. doi: 10.3390/jof7050343

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PQS and C9-PQS inhibit 10AF growth on agar. Effects of PQS, 3Cl-PQS (3Cl), NH₂-PQS (NH₂), HHQ, and C1-, C3-, C5-, C9-PQS were tested against 10AF growth on RPMI agar. All molecules were tested at 12.5 μg/mL. Only C9-PQS and PQS inhibited significantly (both p < 0.001), compared to control. PQS was more inhibitory compared to C1-PQS, C3-PQS, C5-PQS (all p < 0.001), and to NH₂-PQS, 3Cl-PQS, HHQ (all p < 0.05). PQS and C9-PQS inhibited growth equally.