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. 2021 Apr 23;10(5):513. doi: 10.3390/pathogens10050513

Figure 2.

Figure 2

Schematic diagram of epitopes of anti-PrP antibodies used in this study. Epitopes on the mature human full-length PrP sequence from 23–231: anti-N: PrP23–40; 12B2: PrP90–94; Tohoku 2 (T2): PrP97–103; 1E4: PrP97–105; 9A2: PrP99–101; 3F4: PrP106–112; V14: PrP168–181; Bar209: PrP185–196; EP1802Y: PrP217–226; and anti-C: PrP220–231. Red font: antibodies with high affinity to the intermediate fragments VPSPr PrPres; blue font: antibodies with high affinity to C-terminal fragments. Red triangle: binding sites for intermediate VPSPr PrPres bands; Blue triangle: binding site for C-terminal VPSPr PrPres bands.