Table 2: Binding and biological activity parameters for SCTR mutant constructs expressed in COS-1 cells.
Constructs | pKi | pEC50 |
---|---|---|
SCTR WT | 9.2±0.2 | 11.6±0.4 |
SCTR (K317C) | 8.7±0.1 | 10.9±0.4 |
SCTR (K317A) | 8.9±0.1 | 10.5±0.2 |
Constructs | pKi | pEC50 |
---|---|---|
SCTR WT | 9.2±0.2 | 11.6±0.4 |
SCTR (K317C) | 8.7±0.1 | 10.9±0.4 |
SCTR (K317A) | 8.9±0.1 | 10.5±0.2 |