Figure 4.

Concentrations (log10) of cytokines ((A), IL1β; (B), IL6; (C), CXCL8; (D), IL10), in uterine fluid of mares susceptible to persistent breeding induced endometritis. Assessments were carried out from pre- (0 h, early onset of estrus), 6, and 24 h post-breeding. Mares (n = 6) had estrous cycles (n = 18) assigned to receive four intrauterine infusions with Lactate Ringer’s Solution (Control, n = 6), platelet-rich (PRP n = 6), or -poor plasma (PPP n = 6) in a crossover design. Different superscripts denote the effects of time (^a,b,c). Asterisk (*) denotes difference between control- and PRP-assigned cycles (p < 0.05).