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. 2021 Apr 29;13(5):799. doi: 10.3390/v13050799

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Conversion patterns of 2nd tat exon CGIs in proviruses from PBMCs and LNMCs from donors 1079, 1683, and 2669. (A) The difference between the levels of conversion between PBMCs (29%) and LNMCs (17%) was significant in PID 1079, p = 0.0009. (B,C) PID 1683 and PID 2669 resulted in similar levels of non-conversion between PBMCs and LNMCs, p = 0.08 and 0.13, respectively. Non-conversion rates of CpG sites were significantly above the assay background of unconverted cytosines at non-CpG sites in all samples (p = 0.0001).