Figure 8.

(A) Conversion patterns of second tat exon CGIs in proviruses extracted from PBMCs and LNMCs from Patient 1. Comparison of the percentage of non-conversion of CpG dinucleotides in the tat/rev/env overlap region of Patient 1 in PBMCs (top panel) and LNMCs (bottom). Note that the difference between all PBMCs and LNMCs was significantly different (p = 0.0001). (B) Conversion profiles of individual CGIs in each single genome from Patient 1 PBMCs and LNMCs. The absence of a dot in a row indicates that the CpG predicted by the consensus sequence was not present in the specific sequence in question. The red stars indicate sequences that are consistent with that of the AMBI-1 clone.