Table 6.
Bone parameters by tertile of plasma Saturated Fatty Acids (SFA).
| Plasma Total SFA Tertiles | |||||
|---|---|---|---|---|---|
| Total Sample (n = 301) | Lowest (<65.35) (n = 99) | Middle (65.35–69.28) (n = 100) | Highest (>69.28) (n = 102) | ||
| Median (IQR); n (%) | Median (IQR); n (%) | Median (IQR); n (%) | Median (IQR); n (%) | p Value | |
| Quantitative Bone Ultrasound | |||||
| BUA (dB/MHz) | 106 (14) | 107 (12) | 106 (13) | 105 (16) | 0.604 |
| SOS (m/s) | 1541 (35) | 1549 (35) | 1540 (31) | 1540 (32) | 0.052 |
| Volumetric BMD (mg/cm3) | |||||
| Total density (mg/cm3) | 305.7 (73.7) | 302.4 (68.4) | 303.2 (71.5) | 308 (80.7) | 0.726 |
| Trabecular density (mg/cm3) | 163.1 (55.4) | 163.4 (50) | 162.4 (60.8) | 164.3 (60.6) | 0.902 |
| Cortical density (mg/cm3) | 418 (109.9) | 414 (109.7) | 419 (109.4) | 426.5 (117.4) | 0.653 |
| Bone morphometry (mm2) | |||||
| Total area (mm2) | 300.4 (54) | 296.9 (48.4) | 303.1 (53.6) | 302 (53.2) | 0.154 |
| Trabecular area (mm2) | 135.1 (24.4) | 133 (21.6) | 136.4 (24.2) | 136 (22.2) | 0.135 |
| Cortical area (mm2) | 165.3 (29.9) | 163.6 (26.8) | 166.7 (29.4) | 166.6 (27.5) | 0.142 |
| Bone Mineral Density | |||||
| BMD L2-L4 (g/cm2) | 0.912 (0.205) | 0.901 (0.18) | 0.917 (0.204) | 0.926 (0.225) | 0.738 |
| BMD L2 (g/cm2) | 0.901 (0.204) | 0.88 (0.186) | 0.894 (0.188) | 0.922 (0.213) | 0.862 |
| BMD L3 (g/cm2) | 0.925 (0.229) | 0.913 (0.204) | 0.925 (0.225) | 0.946 (0.241) | 0.776 |
| BMD L4 (g/cm2) | 0.914 (0.204) | 0.896 (0.171) | 0.919 (0.223) | 0.924 (0.225) | 0.709 |
| Z-score (lumbar spine) | 0.3 (1.6) | 0.1 (1.4) | 0.3 (1.5) | 0.4 (1.9) | 0.697 |
| T-score (lumbar spine) | −1.3 (2) | −1.4 (1.7) | −1.3 (1.9) | −1.2 (2.2) | 0.727 |
| BMD Femoral trochanter (g/cm2) | 0.759 (0.13) | 0.756 (0.157) | 0.757 (0.121) | 0.771 (0.149) | 0.715 |
| BMD Femoral neck (g/cm2) | 0.611 (0.139) | 0.607 (0.135) | 0.609 (0.137) | 0.625 (0.145) | 0.486 |
| Z-score (hip) | 0.5 (1.4) | 0.5 (1.6) | 0.5 (1.2) | 0.5 (1.5) | 0.751 |
| T-score (hip) | −0.8 (1.3) | −0.8 (1.4) | −0.7 (1.1) | −0.7 (1.6) | 0.664 |
| Bone health | |||||
| Normal | n = 103 (34.2%) | n = 29 (28.2%) | n = 33 (32%) | n = 41 (39.8%) | 0.100 |
| Osteopenia | n = 145 (48.2%) | n = 57 (39.3%) | n = 49 (33.8%) | n = 39 (26.9%) | |
| Osteoporosis | n = 53 (17.6%) | n = 13 (24.5%) | n = 18 (34%) | n = 22 (41.5%) | |
Between-group comparisons were performed using the Kruskal Wallis test or the Chi-square test as appropriate. SFA (Saturated Fatty Acid: C8:0 Caprylic acid, + C10:0 Decanoic acid, + C12:0 Lauric acid, + C14:0 Myristic acid, + C16:0 Palmitic acid, + C18:0 Stearic acid, + C20:0 Arachidic acid, + C22:0 Docosanoic acid, + C24:0 Lignoceric acid).