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. 2021 Apr 29;9(5):435. doi: 10.3390/vaccines9050435

Table 1.

The study population basic characteristics. Abbreviations: NSAIDs: nonsteroidal anti-inflammatory drugs.

Parameter Value
Sex
Female
Male
 
15 (55.6%)
12 (44.4%)
Age (mean ± standard deviation; median) 54.44 ± 19.20; 55
Pre-vaccine autoimmune/rheumatic history
None
Rheumatoid Arthritis
Behçet’s disease
Systemic lupus erythematosus (SLE)/SLE-like
Pericarditis
Others
 
6 (22.2%)
6 (22.2%)
4 (14.8%)
3 (11.1%)
2 (7.4%)
6 (22.2%)
Vaccine
BNT-162b2
mRNA-1273
ChAdOx1
 
23 (85.2%)
2 (7.4%)
2 (7.4%)
2nd Vaccine
Administered
Not administered yet
 
12 (44.4%)
15 (55.6%)
Days from vaccine to flare/new-onset
After 1st dose
After 2nd dose
 
21/27 (77.8%); median 4 days [1–25 days]
8/12 (66.7%); median 4 days [1–7 days]
Flare
New-onset
17 (63.0%)
10 (37.0%)
Severity
Mild
Moderate
Severe
 
6 (22.2%)
14 (51.9%)
7 (25.9%)
Therapy
Glucocorticoids
Colchicine
NSAIDs
Plasma exchange
Hydroxychloroquine
Rituximab
Local steroids
Pyridostigmine
Combination of drugs
No additional treatment
 
21 (77.8%)
4 (14.8%)
3 (11.1%)
2 (7.4%)
1 (3.7%)
1 (3.7%)
1 (3.7%)
1 (3.7%)
7 (25.9%)
1 (3.7%)
Response
Rapid response
Spontaneous resolution
Slow response
Intubation
 
21 (77.8%)
2 (7.4%)
2 (7.4%)
1 (3.7%)