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Celastrol and Triptolide attenuate expression of stem cell markers in TNBC cells. The two compounds inhibit cancer stem cells marker, DCLK1, ALDH1, and CD133 protein expression as compared to control, untreated cells in both 2D culture (left panel) and mammosphere cultures (right panel). (A) MDA-MB-231, (B) BT20, and (C) PD-TNBC.
