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Structure of inhibitors that bind to the G-site of GST proteins. (A) 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX), (B) ethacrynic acid, (C) LAS17, and (D) MC3181 (2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol), an NBDHEX analogue.
