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Influenza A virus replication and host factors involved in influenza A virus RNA synthesis. Schematic of IAV replication cycle. Key host factors that play a role in viral RNA synthesis are indicated in green. The green arrows point to the step of the replication cycle that is promoted by the corresponding host factor. The viral proteins PB1, PB2 and polymerase acidic PA are coloured bright blue, dark blue and grey blue, respectively.
