Table 2.
Control | Nintedanib | P Value | |
---|---|---|---|
N = 30 | N = 30 | ||
Ventilator-free days within 28 days | 12 (0–17) | 17 (0–21) | 0.038 |
Percentage of high-attenuation areas on CT | |||
Induction of mechanical ventilation (%) | 29.1 (20.3–33.1) | 30.8 (20.9–46.7) | 0.651 |
Liberation from mechanical ventilation (%) | 38.7 (20.9–45.6) | 25.7 (9.4–34.6) | 0.027 |
Gastrointestinal adverse events | |||
Mild events | 27 (90%) | 25 (83.3%) | 0.448 |
Moderate events | 6 (20%) | 9 (30%) | 0.371 |
Severe events | 3 (10%) | 2 (6.7%) | 0.640 |
Acute liver failure | |||
Mild | 20 (66.7%) | 24 (80%) | 0.243 |
Moderate | 6 (20%) | 11 (36.7%) | 0.158 |
Severe | 2 (6.7%) | 2 (6.7%) | 1.00 |
CT, computed tomography.