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. 2021 Apr 26;13(5):1465. doi: 10.3390/nu13051465

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Change in plasma biomarkers after weight loss and remission of type 2 diabetes. Data are presented as median (IQR) except for GDF-15 (mean ± SEM). (A): FGF-21, (B): GDF-15, (C): Leptin, (D): Adiponectin. There were 29 participants (12 responders/17 non-responders) studied at baseline, 2, and 6 months post-weight loss. FGF-21 Data for one responder is missing (n = 11). * p < 0.05 vs. 0 month, ** p < 0.01 vs. 0 month, *** p < 0.001 vs. 0 month. # p < 0.05 vs. non-responders, ## p < 0.05 vs. non-responders.