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. 2021 Apr 27;10(5):526. doi: 10.3390/pathogens10050526

Table 1.

Clinical characteristics of participants.

HIV-Negative Subjects HIV-1-Positive Subjects
ART-Naive ART-Suppressed Elite Controllers
n = 9 n = 9 n = 10 n = 9
Viral load
(log10 copies/mL)
NA 3.97 ± 1.074 <1.7 <1.7
Years of infection NA 2.11 ± 1.16 8.50 ± 3.44 b*** 12.33 ± 3.44b ***c*
CD4 (cells/μL) 867.1 ± 186.0 511.6 ± 299.1 a* 710.9 ± 259.9 652.1 ± 277.8
CD8 (cells/μL) 420.1 ± 127.1 898.0 ± 387.3 a** 795.0 ± 227.6 a* 562.8 ± 255.0
CD4/CD8 ratio 2.17 ± 0.56 0.68 ± 0.52 a*** 0.93 ± 0.32 a*** 1.38 ± 0.61 a*b*
Age (years) 40.78 ± 8.37 34.00 ± 7.95 47.3 ± 9.94 b** 48.44 ± 7.53 b**

Clinical characteristics of patients. All clinical parameters are reported as mean ± SD. a p value vs. healthy subjects; b p value vs. ART-naive subjects; c p value vs. ART-suppressed subjects; * p < 0.05; ** p < 0.01; *** p < 0.001 (ANOVA, Tukey post-test), NA: not applicable.