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. 2021 Apr 28;11(5):800. doi: 10.3390/diagnostics11050800

Table 1.

A literature-informed summary of resistance mechanisms described in Gram-negative urinary isolates.

ESBL AmpC Carbapenemases Aminoglycoside Resistance Mechanisms Fluoroquinolone Resistance Mechanisms References
(Sorted Alphabetically)
Escherichia Coli CTX-M-1 CTX-M-3
CTX-M-14
CTX-M-9
CTX-M-15
CTX-M-27
CTX-M-30
SHV-7
OXA-1
TEM-21
TEM-22
TEM-28
IRT-3
SHV-12
CMY-2 KPC
VIM
IMP
OXA-48
Efflux pumps
aacC2 qnrA, qnrB, qnrS, mutations in gyrA and parC genes Arpin, 2003
Blazquez, 1993
Bohnert, 2006
Bou, 2002
Bradford, 1996
Kim, 2020
Onanuga, 2019
Rodrigez-Bano, 2004
Teshager, 2000
Yasufuku, 2011
Klebsiella Pneumoniae CTX-M-15
SHV-2
SHV-2a
SHV-5
TEM-15
TEM-19
TEM-21
TEM-24
TEM-48
DHA-1
FOX
CMY-2
KPC
VIM
IMP
OXA-48
16S rRNA methylases: rmtA, rmtB, armA
aadB
aadA2
qnrA, qnrB, qnrS, mutations in gyrA and parC genes Arpin, 2003
Bedenić, 1998
Bedenić, 2001
Bedenić, 2010
Damjanova, 2007
Damjanova, 2008
Gniadkowski, 1998
Gruteke, 2003
M’Zali, 1995
Podbielski, 1991
Thomson, 1991
Vedet, 2006
Zujić-Atalić, 2014
Enterobacter spp. CTX-M-15
CTX-M-10
VEB-1
Derepressed AmpC VIM-1 Apfalter, 2002
Franolić-Kukina, 2016
Girlich, 2001
Proteus spp. TEM-52 CMY-16 Bedenić, 2016
Sardelić, 2010
Klebsiella Aerogenes TEM-3
TEM-24
Arpin, 2003
Citrobacter spp. CTX-M-2
CTX-M-14
CTX-M-15
SHV-12
qnrB4
qnrS
AAc6-Ib-cr
Kanamori, 2011
Acinetobacter Baumannii OXA-23
OXA-24
OXA-58
16S rRNA methylases: armA, rmtB mutations in gyrA and parC genes Franolić-Kukina, 2011
Garneau-Tsodikova, 2016
Ladavac, 2015
Pournaras, 2006
Vranić-Ladavac, 2014
Pseudomonas
Aeruginosa
OXA-10
OXA-17
SHV -5
VIM-2 16S rRN
Amethylases:
armA, rmtA, rmtB, rmtD1, rmtG
aacC6
mutations in gyrA and parC genes Bošnjak, 2010
Bubonja-Šonje, 2015
Garneau-Tsodikova, 2016
Poirel, 2004
Sardelić, 2012
Sorour, 2008