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. 2021 Apr 28;9(5):953. doi: 10.3390/microorganisms9050953

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Scheme 1 — Stereoselective reduction of an activated C=C double bond catalyzed by ene-reductases (ERs). NAD(P)H acts as an electron donor to reduce the flavin cofactor FMN. EWG: electron withdrawing group.