Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 24;10(5):661. doi: 10.3390/antiox10050661

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Scheme showing the biosynthesis of GSH (A), and the glutathione cycle and transport of constituent amino acids and related substrates (B). Figure 2B is modified from Bachhawat AK, Yadav S. The glutathione cycle: glutathione metabolism beyond the γ-glutamyl cycle. IUBMB Life. 2018 July; 70(7):585–592. doi: 10.1002/iub.1756. Epub 2018 Apr 17. PMID: 29667297. Wiley Publishers [19]. GCL—glutamate–cysteine ligase, GS—glutathione synthetase, GSH—glutathione. 5-OP-5-oxoproline. Numbers refer to representative transporters involved. 1–2. MRP family; 3. EAATS family; 4. Peptide transporters; 5–6. System Xc⁻ and other transporters; 7. Glycine transporter; 8. Disulfide transporter.