Histogram displaying relationship between antibody reciprocal titer and epitope coverage in Cohort 3. (A) Average antibody reciprocal titer for different ethnic groups and disease severities. (B) Average epitope coverage for different ethnic groups and disease severities. Pairwise comparisons were made using a one-way ANOVA, and p-values were calculated using Welch’s correction to compare the mean of each category with each other category. Sample sizes: Middle Eastern (other) mild: n = 2, severe: n = 6. Middle Eastern (Qatari) mild: n = 12, severe: n = 3. South Asian mild: n = 30, severe: n = 34. Other mild: n = 5, severe: n = 7.