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. 2021 Apr 25;10(5):668. doi: 10.3390/antiox10050668

Table 4.

Studies employing zebrafish to assess the anti-inflammatory activity of flavonoids.

Ref. Flavonoid Model Effects
[98] chalcone transgenic zebrafish affected wound-induced neutrophil recruitment, Mpx enzymatic activity, protein expression levels of Mpx, NF-κB, and TNF-α
[103] wogonin zebrafish model of sterile tissue injury neutrophil apoptosis blocked by caspase inhibition
[104] quercetin pentylenetetrazole-treated zebrafish decrease in lipid peroxidation together with an antioxidant role, and reduced glutathione

Mpx: myeloperoxidase; NF-κB: nuclear factor kappa B; TNF-α: tumor necrosis factor alpha.