Table 1.
Aggregate and Stage-Stratified Crude 5-Year Overall Survival Probabilities of Non-Small Cell Lung Cancer Patients Who Underwent Surgery According to Facility Type, Adjusted for Patient-Level Variables
| Variable | Community Cancer Program (n = 10,597) | Comprehensive Community Cancer Program (n = 71,271) | Integrated Network (n = 15,849) | Academic Cancer Program (n = 37,047) | NCI Program/Network (n = 18,139) |
|---|---|---|---|---|---|
| No. of deaths | 4,345 | 25,975 | 5,484 | 12,073 | 4,964 |
| 5-yr overall survival | 0.52 (0.51-0.53) | 0.56 (0.56-0.57) | 0.58 (0.57-0.59) | 0.60 (0.59-0.61) | 0.66 (0.65-0.66) |
| By tumor size, cm | |||||
| ≤ 3 (n = 97,143) | 0.57 (0.56-0.59) | 0.62 (0.61-0.63) | 0.64 (0.63-0.65) | 0.66 (0.65-0.67) | 0.73 (0.72-0.73) |
| > 3-5 (n = 36,238) | 0.47 (0.44-0.49) | 0.50 (0.49-0.51) | 0.51 (0.49-0.52) | 0.52 (0.51-0.53) | 0.57 (0.55-0.59) |
| > 5-7 (n = 11,802) | 0.39 (0.35-0.42) | 0.42 (0.41-0.44) | 0.48 (0.45-0.51) | 0.46 (0.44-0.48) | 0.49 (0.45-0.52) |
| > 7 (n = 7,171) | 0.31 (0.26-0.35) | 0.34 (0.32-0.36) | 0.32 (0.29-0.36) | 0.40 (0.38-0.43) | 0.42 (0.38-0.45) |
| By clinical stage | |||||
| I (n = 91,309) | 0.58 (0.57-0.59) | 0.62 (0.62-0.63) | 0.64 (0.63-0.65) | 0.67 (0.0.66-0.68) | 0.71 (0.70-0.72) |
| II (n = 15,296) | 0.36 (0.33-0.40) | 0.43 (0.41-0.44) | 0.46 (0.43-0.49) | 0.47 (0.45-0.49) | 0.52 (0.49-0.55) |
| IIIA (n= 6,634) | 0.28 (0.23-0.33) | 0.34 (0.32-0.36) | 0.34 (0.29-0.39) | 0.37 (0.34-0.40) | 0.42 (0.38-0.46) |
| Unknown (n = 39,664) | 0.49 (0.47-0.51) | 0.50 (0.50-0.51) | 0.53 (0.52-0.55) | 0.54 (0.53-0.55) | 0.62 (0.0.60-0.63) |
| By pathologic stage | |||||
| I (n = 102,674) | 0.60 (0.58-0.61) | 0.63 (0.63-0.64) | 0.65 (0.64-0.66) | 0.67 (0.67-0.68) | 0.73 (0.72-0.74) |
| II (n = 26,837) | 0.37 (0.35-0.40) | 0.42 (0.41-0.43) | 0.46 (0.44-0.48) | 0.47 (0.45-0.48) | 0.53 (0.51-0.55) |
| III (14,128) | 0.27 (0.24-0.31) | 0.32 (0.31-0.33) | 0.34 (0.31-0.37) | 0.34 (0.32-0.36) | 0.41 (0.38-0.44) |
| IV (n = 1,734) | 0.23 (0.16-0.31) | 0.23 (0.20-0.26) | 0.27 (0.20-0.34) | 0.29 (0.25-0.34) | 0.34 (0.27-0.40) |
| Unknown (n = 7,530) | 0.48 (0.44-0.52) | 0.54 (0.0.52-0.56) | 0.56 (0.51-0.60) | 0.57 (0.54-0.60) | 0.60 (0.56-0.64) |
| By pathologic nodal status | |||||
| pN0 (n = 115,337) | 0.59 (0.57-0.60) | 0.62 (0.62-0.63) | 0.64 (0.63-0.65) | 0.66 (0.65-0.67) | 0.71 (0.70-0.72) |
| pN1 (n = 19,405) | 0.32 (0.29-0.34) | 0.38 (0.37-0.39) | 0.41 (0.38-0.43) | 0.42 (0.0.41-0.44) | 0.50 (0.47-0.52) |
| pN2 (n = 10,915) | 0.26 (0.22-0.0.30) | 0.30 (0.29-0.32) | 0.32 (0.29-0.36) | 0.31 (0.29-0.33) | 0.39 (0.36-0.42) |
| pN3 (n = 69) | 0.15 (0.01-0.45) | 0.36 (0.16-0.56) | 0.17 (0.008-0.52) | 0.38 (0.15-0.61) | 0.32 (0.05-0.65) |
| pNX (n = 7,177) | 0.45 (0.41-0.49) | 0.49 (0.47-0.51) | 0.53 (0.49-0.58) | 0.53 (0.50-0.55) | 0.57 (0.52-0.62) |
Data are presented as No. or overall survival probability (95% CI). NCI = National Cancer Institute; pN0 = pathologic node-negative; pNX = resection without lymph node examination. P < .0001 for all survival comparisons.