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. 2020 Nov 14;159(4):1630–1641. doi: 10.1016/j.chest.2020.10.075

Table 4.

Survival Probabilities With Adjusted Hazard Ratios in Those Who Had Potential Poor-Quality Metricsa

Variable 5-Year OS Unadjusted HRb Adjusted HRb
Positive margin (n = 152,903) 0.32 (0.31-0.33) vs 0.59 (0.59-0.60) 2.38 (2.31-2.46) 2.03 (1.96-2.09)
Wedge resection (n = 152,903) 0.53 (0.52-0.53) vs 0.59 (0.58-0.59) 1.17 (1.14-1.20) 1.20 (1.17-1.23)
pNX (n = 122,514) 0.50 (0.49-0.52) vs 0.64 (0.64-0.64), pN0 1.54 (1.48-1.60) 1.48 (1.43-1.54)
< 10-lymph node resection among pathologic stage I-IIc (n = 120,693) 0.61 (0.60-0.61) vs 0.63 (0.62-0.63) 1.06 (1.04-1.09) 1.07 (1.05-1.09)
Non-evidence-based use of adjuvant radiation therapyd (n = 129,412) 0.41 (0.39-0.42) vs 0.62 (0.62-0.63) 1.97 (1.88-2.06) 1.70 (1.62-1.78)
Non-evidence-based use of adjuvant chemotherapye (n = 101,561) 0.64 (0.63-0.66) vs 0.66 (0.65-0.66) 1.05 (1.01-1.09)f 1.11 (1.07-1.16)

Data are presented as OS (95% CI) or HR (95% CI). HR = hazard ratio; OS = overall survival; pN0 = pathologic node-negative; pNX = resection without lymph node examination.

a

Hazard ratios adjusted for age at diagnosis, race or ethnicity, sex, year of diagnosis, insurance, geographic region of the facility, comorbidity score, and clinical stage.

b

P < .0001 unless otherwise stated.

c

Among patients with pathologic stage I-II, including patients with 0 lymph nodes, excluding patients with unknown number of nodes.

d

Patients with pathologic N0 and N1 and negative resection margins.

e

Patients with pathological stage I with tumor size ≤ 4 cm and negative resection margins.

f

P = .0238.