Skip to main content
. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: FASEB J. 2020 Jul 1;34(8):10920–10930. doi: 10.1096/fj.201903093R

Figure 3. The effects of MβCD treatment on cannabinoid modulation of GlyR gating kinetics.

Figure 3.

(a-c) Influence of THC on activation (a), deactivation (b) and desensitization (c) time of α1WT or α1S296A mutant GlyR expressed in HEK 293T cells after vehicle, MβCD or MβCD+1.0 mM cholesterol pretreatment. All digits in the columns represent numbers of cells tested. Data are represented as mean ± SEM. *P<0.05, **P<0.01 based on unpaired t-tests with Welch’s correction.