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. 2021 Apr 30;11(5):678. doi: 10.3390/biom11050678

Figure 3.

Figure 3

Chronic stress-induced dysbiosis leads to Alzheimer’s pathology. Chronic stressors, such as altered food pattern, sleep architecture, and bacterial infections, change the microbiome and alter microbiota. The state of dysbiosis may progress to pathological changes (NFTs, Aβ), leading to the development of Alzheimer’s disease. H. Pylori; Helicobacter pylori; Il-Interleukins; TLR; Toll like receptor; LPS; Lipopolysaccharides; MAMP: Microbe-Associated Molecular Pattern.