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SDF1, CXCR4 and MMP12 expression in murine atherosclerotic aortas. (a) mRNA levels of SDF1 in aortas of Apoe-/- and Apoe-/-Mmp10-/- (2KO) mice at 10 and 16 months of age (n = 5/time point). (b) Aortic expression of CXCR4 was decreased in 2KO mice (n = 5/time point) vs. Apoe-/- at 16 months. (c) 2KO presented a reduction of MMP12 (n = 5/time point) vs. Apoe-/- at 10 months. * p < 0.05.
