Table 2.
Characteristics and in vitro antifungal susceptibility profiles of azole-resistant Aspergillus spp. isolates (n = 6) from clinical samples.
| Isolate | Species | Origin | Sample Type | MIC (mg/L) | cyp51A Gene | |||
|---|---|---|---|---|---|---|---|---|
| VCZ | ITZ | PCZ | ISA | |||||
| Af 001 | A. fumigatus | Patient | BAL 1 | 2 | 1 | 0.25 | 1 | WT 3 |
| Af 002 | A. fumigatus | Patient | BAL 1 | 0.5 | >8 | >8 | 1 | G54R |
| Af 003 | A. fumigatus | Patient | BAL 1 | 4 | >8 | 1 | 8 | TR34/L98H |
| Af 004 | A. fumigatus | Patient | BAL 1 | 2 | 2 | 1 | 4 | WT 3 |
| At 001 | A. terreus | Patient | BA 2 | >8 | 1 | 1 | >8 | WT 3 |
| At 002 | A. terreus | Patient | BA 2 | 2 | 1 | 0.5 | 4 | WT 3 |
1 BAL: Broncho-alveolar lavage; 2 BA: Bronchial aspiration; 3 WT: Wild-Type.