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. 2021 Apr 30;9(5):496. doi: 10.3390/biomedicines9050496

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Prevalence of MCT8-aAb and MCT10-aAb in thyroid patients. (A) A cohort of adult patients with different thyroid diseases (n = 318) were analyzed for the presence of MCT8-aAb and MCT10-aAb, respectively. Several highly positive serum samples were identified, surpassing the diagnostic threshold. (B) Separating the patients according to their primary diagnosis into Graves’ disease (MB), Hashimoto’s thyroiditis (HT) and other thyroid diseases (other) indicated positive samples in all disease groups with no apparent disease-specific prevalence for MCT8-aAb or MCT10-aAb. The binding index (BI) is indicated along with the threshold for positivity (broken horizontal line), i.e., the value representing P75 + 1.5 × IQR of the full study cohort.