Table 2.
ATIP3 localization and function in human and Xenopus cells.
| Human ATIP3 | Reference | Xenopus ICIS | Reference | |
|---|---|---|---|---|
| Localization | Microtubule Mitotic Spindle Centrosome |
[19] | Centromere Centrosome |
[55] |
| Interacts with | EB1 KIF2A DDA3 |
[49,51] | XKCM1 KIF2A AURKB INCENP TD-60 |
[55,56] |
| Signaling | ERK AURKA KIF2C CDC25B CDK1 |
[4,32,51,57] | ||
| Function | Microtubule dynamics Spindle size Centrosome number Proliferation Migration Polarization EMT |
[19,21,32,49,51,57,58] | Microtubule dynamics Mitotic spindle integrity |
[55,56] |