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Influence of medium proteins in miRNA adsorption on MSN-NH2. (A) miR-200c adsorption in the presence of a small protein (Apo AII), a large protein (C3c), or a small and a large protein (Apo AII + C3c). (B) Effect of PEGylation of nanoparticle surface on the adsorption of miR-200c in the absence and presence of a small and a large protein (Apo AII + C3c). Data are expressed as the mean ± SD. Statistics: * p < 0.05; ** p < 0.01; **** p < 0.0001; ***** p < 0.00001.
