Table 2.
UGT1As regulated by miRNAs
| miRNAs | Target cells | Target UGT1As | References |
|---|---|---|---|
| miR-21-3p, miR-103p, miR-141-3p, miR-200a-3p, miR-376b-3p | LS180 | UGT1A1, UGT1A6 | [77] |
| miR-21-3p, miR-141-3p, miR-200a-3p | Human hepatocytes | UGT1A1, 4, 6, 9 | [77] |
| miR-141-3p | HEK-293 | UGT1A1, 3, 4, 6, 7, 9 | [80] |
| miR-141-3p | HuH-7 | UGT1A1, 4, 6, 8, 10 | [80] |
| miR-141-3p | CaCo2 | UGT1A1, 4, 6, 9 | [80] |
| miR-491-3p | HuH-7 | UGT1A1, 3, 6 | [81] |
| miR-491-3p | Human hepatocytes (western counties) | UGT1A3, UGT1A6 | [81] |
| miR-491-3p | Human hepatocytes (Chinese Han population) | UGT1A3, UGT1A4 | [82] |
| miR-298 | LS174T | UGT1A1, 3, 4, 9 | [82] |
| miR-298 | Human liver tissues | UGT1A3, UGT1A4 | [82] |
| miR-548d-5p | Human hepatocytes | UGT1A1 | [83] |
| miR-548d-5p | HepG | UGT1A1 | [83] |
| miR-200a-3p, miR-183-5p | HCC | UGT1A9 | [84] |
| miR-375 | LS180 | UGT1A1, UGT1A6 | [85] |
| miR-375 | Human hepatocytes | UGT1A | [85] |