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. 2021 May 2;11(5):684. doi: 10.3390/biom11050684

Table 2.

Inflammatory markers according to endoscopic + histological severity index before and after stimulation.

Severity Index Serum CRP
Stimulated Group (n = 34) Control Group (n = 35)
n * Me RI n Me RI
Pre-stimulation Severe 9 11.03 ±4.9 9 12.16 ±3.14
Moderate 21 10.51 ±3.37 23 10.1 ±1.96
Mild 4 5.27 ±0.37 3 7.83 ±1.53
Post-stimulation Severe - - 9 11.96 ±2.91
Moderate 3 7.35 ±3.06 23 9.95 ±2.09
Mild 19 3.8 ±1.72 3 7.67 ±1.33
Absent 12 4.2 ±1.03 - -
NLR ratio
Pre-stimulation Severe 9 3.17 ±1.53 9 2.92 ±0.65
Moderate 21 3.01 ±1.1 23 2.87 ±0.32
Mild 4 2.58 ±0.94 3 2.62 ±0.47
Post-stimulation Severe - - 3 2.98 ±0.73
Moderate 3 1.97 ±0.85 23 2.83 ±0.30
Mild 19 1.7 ±0.46 3 2.54 ±0.45
Absent 12 2.39 ±1.28 - -
LMR ratio
Pre-stimulation Severe 9 4.82 ±0.63 9 4.99 ±0.31
Moderate 21 4.24 ±0.31 23 4.62 ±1.47
Mild 4 3.96 ±1.17 3 4.44 ±0.30
Post-stimulation Severe - - 9 4.99 ±0.57
Moderate 3 3.75 ±0.36 23 4.31 ±0.27
Mild 19 3.11 ±0.71 3 4.36 ±0.27
Absent 12 3.72 ±1.06 - -
PLR ratio
Pre-stimulation Severe 9 114.74 ±19.79 9 130.37 ±19.27
Moderate 21 121.87 ±20.83 23 134.82 ±9.31
Mild 4 131.76 ±3.56 3 142.08 ±1.95
Post-stimulation Severe - - 9 132.66 ±18.08
Moderate 3 154.50 ±26.07 23 134.57 ±8.16
Mild 19 158.37 ±3.56 3 140.99 ±1.84
Absent 12 153.61 ±31.31 - -
Serum Transferrin
Pre-stimulation Severe 9 174.66 ±43.14 9 174.55 ±10.51
Moderate 21 184.96 ±32.01 23 184.34 ±10.09
Mild 4 196.60 ±17.53 3 211.66 ±21.50
Post-stimulation Severe - - 9 174.11 ±9.08
Moderate 3 248.66 ±68.82 23 182.39 ±11.05
Mild 19 252.01 ±42.32 3 217.33 ±38.07
Absent 12 232.25 ±35.53 - -

To describe the quantitative variables, the median (Me) and interquartile range (RI) were used. CRP: C-reactive protein. NLR (neutrophil-to-lymphocyte ratio). LMR (lymphocyte-to-monocyte ratio). PLR (platelet-to-lymphocyte ratio). n * of the stimulated group changes because the stimulation with probiotics produces a decrease in the endoscopic and histological severity of diversion colitis.