Table 2.
Inflammatory markers according to endoscopic + histological severity index before and after stimulation.
| Severity Index | Serum CRP | ||||||
|---|---|---|---|---|---|---|---|
| Stimulated Group (n = 34) | Control Group (n = 35) | ||||||
| n * | Me | RI | n | Me | RI | ||
| Pre-stimulation | Severe | 9 | 11.03 | ±4.9 | 9 | 12.16 | ±3.14 |
| Moderate | 21 | 10.51 | ±3.37 | 23 | 10.1 | ±1.96 | |
| Mild | 4 | 5.27 | ±0.37 | 3 | 7.83 | ±1.53 | |
| Post-stimulation | Severe | - | - | 9 | 11.96 | ±2.91 | |
| Moderate | 3 | 7.35 | ±3.06 | 23 | 9.95 | ±2.09 | |
| Mild | 19 | 3.8 | ±1.72 | 3 | 7.67 | ±1.33 | |
| Absent | 12 | 4.2 | ±1.03 | - | - | ||
| NLR ratio | |||||||
| Pre-stimulation | Severe | 9 | 3.17 | ±1.53 | 9 | 2.92 | ±0.65 |
| Moderate | 21 | 3.01 | ±1.1 | 23 | 2.87 | ±0.32 | |
| Mild | 4 | 2.58 | ±0.94 | 3 | 2.62 | ±0.47 | |
| Post-stimulation | Severe | - | - | 3 | 2.98 | ±0.73 | |
| Moderate | 3 | 1.97 | ±0.85 | 23 | 2.83 | ±0.30 | |
| Mild | 19 | 1.7 | ±0.46 | 3 | 2.54 | ±0.45 | |
| Absent | 12 | 2.39 | ±1.28 | - | - | ||
| LMR ratio | |||||||
| Pre-stimulation | Severe | 9 | 4.82 | ±0.63 | 9 | 4.99 | ±0.31 |
| Moderate | 21 | 4.24 | ±0.31 | 23 | 4.62 | ±1.47 | |
| Mild | 4 | 3.96 | ±1.17 | 3 | 4.44 | ±0.30 | |
| Post-stimulation | Severe | - | - | 9 | 4.99 | ±0.57 | |
| Moderate | 3 | 3.75 | ±0.36 | 23 | 4.31 | ±0.27 | |
| Mild | 19 | 3.11 | ±0.71 | 3 | 4.36 | ±0.27 | |
| Absent | 12 | 3.72 | ±1.06 | - | - | ||
| PLR ratio | |||||||
| Pre-stimulation | Severe | 9 | 114.74 | ±19.79 | 9 | 130.37 | ±19.27 |
| Moderate | 21 | 121.87 | ±20.83 | 23 | 134.82 | ±9.31 | |
| Mild | 4 | 131.76 | ±3.56 | 3 | 142.08 | ±1.95 | |
| Post-stimulation | Severe | - | - | 9 | 132.66 | ±18.08 | |
| Moderate | 3 | 154.50 | ±26.07 | 23 | 134.57 | ±8.16 | |
| Mild | 19 | 158.37 | ±3.56 | 3 | 140.99 | ±1.84 | |
| Absent | 12 | 153.61 | ±31.31 | - | - | ||
| Serum Transferrin | |||||||
| Pre-stimulation | Severe | 9 | 174.66 | ±43.14 | 9 | 174.55 | ±10.51 |
| Moderate | 21 | 184.96 | ±32.01 | 23 | 184.34 | ±10.09 | |
| Mild | 4 | 196.60 | ±17.53 | 3 | 211.66 | ±21.50 | |
| Post-stimulation | Severe | - | - | 9 | 174.11 | ±9.08 | |
| Moderate | 3 | 248.66 | ±68.82 | 23 | 182.39 | ±11.05 | |
| Mild | 19 | 252.01 | ±42.32 | 3 | 217.33 | ±38.07 | |
| Absent | 12 | 232.25 | ±35.53 | - | - | ||
To describe the quantitative variables, the median (Me) and interquartile range (RI) were used. CRP: C-reactive protein. NLR (neutrophil-to-lymphocyte ratio). LMR (lymphocyte-to-monocyte ratio). PLR (platelet-to-lymphocyte ratio). n * of the stimulated group changes because the stimulation with probiotics produces a decrease in the endoscopic and histological severity of diversion colitis.