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. 2021 May 15;2021:6622342. doi: 10.1155/2021/6622342

Figure 3.

Figure 3

miR-126-5p targets ADAM9 to regulate cisplatin sensitivity in NSCLC: (a) ADAM9 mRNA harbors a miR-126-5p-binding sequence; (b) detection of luciferase activities of the reporter genes (∗∗P < 0.01); (c) qRT-PCR detected the mRNA expression of ADAM9 in sensitive and resistance groups (∗∗∗P < 0.001); (d) qRT-PCR detected the expression of ADAM9 in NSCLC cell lines (∗P < 0.05, ∗∗P < 0.01); (e) detection of ADAM9 mRNAs in the mimics group; (f) (left) western blotting-based detection of the protein expression in the mimics group and (right) quantitative analysis of the gray value of protein bands in the blot (∗∗P < 0.01 vs. NC group).