Skip to main content
. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Mol Immunol. 2021 Jan 15;131:171–179. doi: 10.1016/j.molimm.2020.12.035

Fig 6. Proinflammatory factors generally increased upon TREM2 overexpression in HMC3 cells.

Fig 6.

(1) No change in inflammatory factors after 24 hour Aβ42 treatment. (2) No change in inflammatory factors with TREM2 overexpression. (3) No change in inflammatory factors when TREM2 silenced. (4) No change in inflammatory factors with TREM2 overexpression after 24 hour Aβ42 treatment. (5) FGF-2 is increased and MIP- 1a is decreased when TREM2 silenced after 24 hour Aβ42 treatment. (6) In response to 24 hour Aβ42 treatment TREM2 silencing results in a decrease in IP-10, MIP-1a, IL- 8 and a increase in FGF-2, VEGF, GRO, compared to TREM2 overexpression. (A) Significance (p-values) are Tukey adjusted for multiple comparisons and mean difference (Mean Diff.) is shown for each apoptotic factor. (B)