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. Author manuscript; available in PMC: 2021 May 25.
Published in final edited form as: J Org Chem. 2019 Dec 9;85(3):1725–1730. doi: 10.1021/acs.joc.9b02615

Figure 1.

Figure 1.

Ribbon diagram of the parent WW domain (PDB ID: 1PIN) from which the variants described here were derived. The orange outlined box shows the non-polar residues that we incorporated at positions 12 and 14, which are highlighted in orange space-filling spheres. Shown in parentheses are the c log P values for the corresponding N-acetyl N-methyl amino acid amide. The black outlined box shows the PrF and PrFp residues that we incorporated at position 23, which is highlighted in black space-filling spheres.