Table 1.
Demographic characteristics of all patients with a cMRI both at 2-7 days and at 12 weeks, split into CMV positive and negative (n=48).
| CMV Positive (n=29) | CMV Negative (n=19) | p value | |
|---|---|---|---|
| Age (years) | 67.0 ± 1.9 | 61.6 ± 2.3 | 0.08 |
| Male | 23 (79.3) | 17 (89.5) | 0.45 |
| BMI (kg/m2) | 28.9 ± 0.8 | 26.4 ± 1.8 | 0.16 |
| Past CAD | 2 (6.9) | 1 (5.3) | >0.99 |
| Family history of CAD | 11 (37.9) | 7 (36.8) | >0.99 |
| Hypertension | 5 (17.2) | 3 (15.8) | >0.99 |
| Hypercholesterolaemia | 3 (10.3) | 0 (0) | 0.27 |
| Diabetes mellitus | 2 (6.9) | 2 (10.5) | >0.99 |
| Current smoker | 4 (13.8) | 7 (36.8) | 0.09 |
| Anterior MI | 7 (24.1) | 6 (31.6) | 0.74 |
| Peak troponin (ng/L) | 3804 ± 528 | 4716 ± 747 | 0.37 |
| Acute infarct size (% of LV) | 10.2 ± 1.4 | 13.3. ± 3.0 | 0.60 |
| Pre-admission medication | |||
| Aspirin | 3 (10.3) | 1 (5.3) | >0.99 |
| β-blocker | 1 (3.4) | 1 (5.3) | >0.99 |
| ACE-inhibitor/ARB | 4 (13.8) | 2 (10.5) | >0.99 |
| Diuretic | 3 (10.3) | 1 (5.3) | >0.99 |
| Statin | 8 (27.6) | 2 (10.5) | 0.28 |
| Calcium channel blocker | 3 (10.3) | 2 (10.5) | >0.99 |
| Procedure details | |||
| Onset to balloon time (min) | 191 ± 16.7 | 200 ± 23.3 | 0.95 |
| >1 vessel treated | 3 (10.3) | 3 (15.8) | 0.67 |
| Flow pre-PCI (TIMI 0/1/2/3) | 24/5/0/0 | 17/2/0/0 | 0.69 |
| Flow post-PCI (TIMI 0/1/2/3) | 0/2/0/27 | 0/0/0/19 | 0.51 |
Four further patients were used in detailed lymphocyte analysis, and their inclusion does not meaningfully alter the demographics presented. Continuous variables are presented as mean ± SEM. Discrete variables are presented as count (percentage). p values were determined with the Mann-Whitney U test for continuous variables and Fischer’s exact test for discrete. P values <0.05 were considered statistically significant. BMI, Body Mass Index; CAD, coronary artery disease; ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; TIMI, thrombolysis in myocardial infarction.