Figure 3.

(a) Photothermal effect of different concentrations (50 μM and 100 μM) of sc-PepIR-40 nanotubes under 808 nm laser irradiation, and PBS buffer was used as the control. (b) UV-vis absorption spectra of ABDA under 808 nm laser irradiation for different times in the presence of sc-PepIR-40 nanotubes. Intracellular ¹O₂ generation of sc-PepIR-40 nanotubes in U87MG cells with/without NIR laser irradiation detected by DCFH-DA (c), Rho123 (d), and caspase 3/7 kit (e). Cell nuclei were stained with DAPI in blue color. All laser irradiation was 5 min (808 nm, 1.8 W cm⁻²).