Table 1.
Baseline characteristics before and after propensity score matching in PCNSLs.
| Variable | Before PSM (N/%) | After PSM (N/%) | ||||
|---|---|---|---|---|---|---|
| No evidence | CT | P value | No evidence | CT | P value | |
| N | 527 (26.1) | 1493 (73.9) | 527 (28.8) | 1304 (71.2) | ||
| Age at diagnosis | 0.010 | 0.209 | ||||
| ≤60 years | 192 (36.4) | 642 (43.0) | 192 (36.4) | 518 (39.7) | ||
| >60 years | 335 (63.6) | 851 (57.0) | 335 (63.6) | 786 (60.3) | ||
| Sex | 0.693 | 1.000 | ||||
| Male | 282 (53.5) | 784 (52.5) | 282 (53.5) | 698 (53.5) | ||
| Female | 245 (46.5) | 709 (47.5) | 245 (46.5) | 606 (46.5) | ||
| Race | <0.001 | <0.001 | ||||
| White | 396 (75.1) | 1207 (80.8) | 396 (75.1) | 1057 (81.1) | ||
| Black | 66 (12.5) | 90 (6.0) | 66 (12.5) | 78 (6.0) | ||
| Others# | 65 (12.3) | 196 (13.2) | 65 (12.3) | 169 (13.0) | ||
| Marital status | <0.001 | <0.001 | ||||
| Married | 266 (50.5) | 931(62.4) | 266 (50.5) | 800 (61.3) | ||
| Unmarried | 261 (49.5) | 562 (37.6) | 261 (49.5) | 504 (38.7) | ||
| Year of diagnosis | 0.268 | 0.507 | ||||
| 2004–2009 | 253 (48.0) | 675 (45.2) | 253 (48.0) | 602 (46.2) | ||
| 2010–2015 | 274 (52.0) | 818 (54.8) | 274 (52.0) | 702 (53.8) | ||
| Tumor location | 0.085 | 0.913 | ||||
| Brain | 475 (90.1) | 1290 (86.4) | 475 (90.1) | 1181 (90.6) | ||
| Spine | 14 (2.7) | 57 (3.8) | 14 (2.7) | 36 (2.8) | ||
| NOS* | 38 (7.2) | 146 (9.8) | 38 (7.2) | 87 (6.7) | ||
| Histological Type | 0.036 | 0.155 | ||||
| Mature B-cell NHL | 453 (86.0) | 1334 (89.4) | 453 (86.0) | 1154 (88.5) | ||
| Others$ | 74 (14.0) | 159 (10.6) | 74 (14.0) | 150 (11.5) | ||
| Surgery | 0.431 | 0.816 | ||||
| Yes | 212 (40.2) | 863 (57.8) | 212 (40.2) | 534 (41.0) | ||
| No evidence | 315 (59.8) | 630 (42.2) | 315 (59.8) | 770 (59.0) | ||
#Others include American Indian/Alaska Native and Asian/Pacific Islander.
*Not specific primary site of central nerve system.
$Others include peripheral T-cell lymphoma, anaplastic large cell lymphoma, extranodal NK-/T-cell lymphoma, blastic plasmacytoid dendritic cell neoplasm, precursor B-lymphoblastic lymphoma, precursor T-cell lymphoblastic lymphoma and not specific non-Hodgkin’s lymphoma. The bold values mean P value < 0.05.
CT, Chemotherapy; NOS, not otherwise specific; PSM, propensity score matching.