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. 2021 May 11;11:641955. doi: 10.3389/fonc.2021.641955

Table 3.

Multivariate competing-risks regression analysis of cardiovascular death in PCNSLs.

Variable Before PSM After PSM
HR (95% CI) P Value HR (95% CI) P Value
Unadjusted HR
 Chemotherapy 0.476 (0.262–0.862) 0.014 0.445 (0.240–0.824) 0.010
 No evidence Reference Reference
Model 1 a
 Chemotherapy 0.523 (0.290–0.943) 0.031 0.469 (0.255–0.862) 0.015
 No evidence Reference Reference
Model 2 b
 Chemotherapy 0.519 (0.288–0.933) 0.028 0.473 (0.257–0.870) 0.016
 No evidence Reference Reference
Model 3 c
 Chemotherapy 0.496 (0.274–0.898) 0.021 0.446 (0.241–0.824) 0.010
 No evidence Reference Reference
a

In model 1, hazard ratios were adjusted for statistically significant factors according to univariate analysis (age at diagnosis and year of diagnosis).

b

In model 2, hazard ratios were adjusted for all factors in model 1, plus the potential confounders included in propensity score matching (sex, tumor location, histological type and surgery).

c

In model 3, hazard ratios were adjusted for all factors in model 2, plus the other demographic characteristics (race and marital status).

HR, hazard ratios; PSM, propensity score matching; 95% CI, 95% confidence interval.

The bold values mean P value < 0.05.